Desmond Harrington's career took off with a series of memorable performances that showcased his range as an actor. Some of his most notable roles include:
- Joey Quinn in Dexter: Harrington gained widespread recognition for his role as a detective in the acclaimed series, where he shared the screen with a stellar cast. His character's complex relationship with the lead character added depth to the storyline.
- Chuck Bass's Best Friend in Gossip Girl: In this popular teen drama, Harrington played a pivotal role that resonated with audiences, showcasing his ability to navigate the dynamics of friendships and rivalries.
- Stacy in The Hole: Harrington took on a thrilling role in this horror film, demonstrating his versatility and willingness to tackle different genres.